I can't stand American Dad. Probably because it centers around a constant bashing of Republicanism, which gets pretty old after a while.

Admittedly, the old Family Guy was much better, but the jokes are still solid. Aside from that, there are a few twists that keep it interesting. The characters are more dynamic and have more interesting interactions among themselves.

Brian and Stewie or Klaus and Roger?

Definitely Brian and Stewie. In my opinion, they're what really sets the show apart. Roger comes off as really annoying and strange.

Peeta and Louis or Stan and Francine?

This is more of a toss-up. Peter is great but Lois is one of the weaker characters. Stan and Francine have a good dynamic.

Meg and Chris or Hayley and Steve?

Another toss-up. Meg and Hayley are similar, but Meg provides more humor. Chris is more of a minor character and Steve is probably the strongest character in American Dad.